| Compounds | Topics | Title | Date |
|---|---|---|---|
| Bisabolol | leg ulcers in humans via placebo trial (n=29) | Randomized, controlled study of innovative spray formulation containing ozonated oil and Alpha-bisabolol in the topical treatment of chronic venous leg ulcers. | Sep 2015 |
|
Ingestion Method: topical At the end of treatment, the proportion of patients with complete ulcer healing was higher with ozonated oil and alpha--bisabolol formulation (25% vs 0%). Furthermore, the changes in ulcer surface area were significant for ozonated oil and alpha--bisabolol formulation only (P < .05), in particular, observing a significant and progressive reduction of the wound surface by 34%, 59%, and 73%, after 7, 14, and 30 days of treatment, respectively. | |||